Toxicity assessment of superparamagnetic iron oxide nanoparticles in different tissues
نویسندگان
چکیده
منابع مشابه
Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION)
Superparamagnetic iron oxide nanoparticles (SPION) are being widely used for various biomedical applications, for example, magnetic resonance imaging, targeted delivery of drugs or genes, and in hyperthermia. Although, the potential benefits of SPION are considerable, there is a distinct need to identify any potential cellular damage associated with these nanoparticles. Besides focussing on cyt...
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Much recent research on nanoparticles has occurred in the biomedical area, particularly in the area of superparamagnetic iron oxide nanoparticles (SPIONs); one such area of research is in their use as magnetically directed prodrugs. It has been reported that nanoscale materials exhibit properties different from those of materials in bulk or on a macro scale [1]. Further, an understanding of the...
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Oxide Nanoparticles Morteza Mahmoudi,* Heinrich Hofmann, Barbara Rothen-Rutishauser, and Alke Petri-Fink* Laboratory of Powder Technology, Ecole Polytechnique F ed erale de Lausanne, Lausanne, Switzerland (http://ltp.epfl.ch) National Cell Bank, Pasteur Institute of Iran, Tehran, Iran (www.biospion.com) Institute for Nanoscience and Nanotechnology Research Center, Faculty of Pharmacy, Tehran Un...
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The uptake and distribution of negatively charged superparamagnetic iron oxide (Fe₃O₄) nanoparticles (SPIONs) in mouse embryonic fibroblasts NIH3T3, and magnetic resonance imaging (MRI) signal influenced by SPIONs injected into experimental animals, were visualized and investigated. Cellular uptake and distribution of the SPIONs in NIH3T3 after staining with Prussian Blue were investigated by a...
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Nanoparticles that are aimed at targeting cancer cells, but sparing healthy tissue provide an attractive platform of implementation for hyperthermia or as carriers of chemotherapeutics. According to the literature, diverse effects of nanoparticles relating to mammalian reproductive tissue are described. To address the impact of nanoparticles on cyto- and genotoxicity concerning the reproductive...
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ژورنال
عنوان ژورنال: Artificial Cells, Nanomedicine, and Biotechnology
سال: 2020
ISSN: 2169-1401,2169-141X
DOI: 10.1080/21691401.2019.1709855